Scientific Articles

Cognitive Support

1) Effects of the Aphanizomenon flos-aquae Extract (Klamin®) on a Neurodegeneration Cellular Model. D. Nuzzo , G. Presti, P. Picone,G. Galizzi,E. Gulotta, S. Giuliano, C. Mannino, V. Gambino, S. Scoglio, and M. Di Carlo. Oxidative Medicine and Cellular Longevity. Volume 2018.

2) Study on the effects of super blue-green algae on the nutritional status and school performance of first, second and third grade children.Sevilla I, Aguirre N.The Nicaragua Report. Cell Tech; 1995.

Healthy Aging
Immune Health

1) Wild-Harvested AFA Microalgae from Klamath Lake - Cellular and Immune Protection

2) Bioregulatory and therapeutic effects of blue-green algae. Kumar K, Lakshmanan A, and Kannaiyan S. Indian Journal of Microbiology. 2003; 43 (1): 9-16.

3) Isolation of three high molecular weight polysaccharide preparations with potent immunostimulatory activity from Spirulina platensisAphanizomenon flos-aquae, and Chlorella pyrenoidosa. Pugh N, Ross SA, ElSohly HN, ElSohly MA, Pasco DS. Planta Med. 2001; 67: 737-742.

4) Blue-green algae as an immuno-enhancer and biomodulator. Jenson GS, Ginsberg DI, Drapeau C. Journal on Nutraceuticals and Nutrition (JANA). 2001; 3: 24-30.

5) Consumption of Aphanizomenon flos-aquae has rapid effects on the circulation and function of immune cells in humans. Jensen GS, Ginsberg DI, Huerta P, Citton M, Drapeau C. Journal of the American Nutraceutical Association. 2000; 2 (3): 50-58.

6) Effects of the blue-green algae Aphanizomenon flos-aquae (L.) Ralphs on human natural killer cells. Manoukian R, Citton M, Huerta P, et al. Phytoceuticals: Examining the health benefits and pharmaceutical properties of natural antioxidants and phytochemicals. Massachusetts: International Business Communications, Inc.; 1998.

Antioxidant Production/Support
Gut Health

1) Influence of Aphanizomenon flos-aquae and two of its extracts on growth ability and antimicrobial properties of Lactobacillus acidophilus DDS-1. Rafaella campana, Veronica Martinelli, Stefano Scoglio, Evelin Colombo, Serena Benedetti, Wally Baffone. LWT - Food Science and Technology. 81 (2017) 291e298.

2) Alteration of the gastrointestinal microbiota of mice by edible blue-green algae. Rasmussen HE, Martinez I, Lee JY, Walter J. Journal of Applied Microbiology. 2009; 107: 1108-1118.

3) Effect of a Klamath algae product (“AFA-B12”) on blood levels of vitamin B12 and homocysteine in vegan subjects: a pilot study. Baroni L, Scoglio S, Benedetti S, Bonetto C, Pagliarani S, Benedetti Y, Rocchi M, Canestrari F. International Journal for Vitamin and Nutrition Research. 2009 Mar;79(2):117-23. doi: 10.1024/0300-9831.79.2.117.

4) Evaluation of renoprotective effect of Aphanizomenon flos-aquae on cisplatin-induced renal dysfunction in rats. Kuriakose GC, Kurup MG. Renal Failure. 2008; 30: 717-725.

5) The effect of blue-green algae Aphanizomenon flos-aquae on nutrient assimilation in rats. Kushak R, Drapeau C, Winter H. Journal on Nutraceuticals and Nutrition (JANA). 2001; 3:35-39.